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KMID : 0613320010070010013
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Journal of the Korean Bone and Joint Tumor Soceity
2001 Volume.7 No. 1 p.13 ~ p.19
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Malignant Melanoma
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Rhee Seung-Koo
Kang Yong-Koo
Park Won-Jong
Chung Yang-Guk
Lee Hyuk-Je
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Abstract
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Background: The incidence of malignant melanoma is currently increasing at a rate greater than any other cancer occuring in human. At this time, early diagnosis and surgical excision were the mainstay of treatment for patients with
malignant melanoma. We reviewed the results of average 4 years of follow-up after surgical excision of total 16 cases of malignant melanoma since 1985.
Materials and Methods: There were 16 patients (mean age 58.5 years, 5 men, 11 women). The site of the primary lesion was foot and toe (6), back (3), hand (2), thigh (2), shoulder (1), lower abdomen (1) and lip (1). The lymph node was involved at 9 patients. The histologic diag-nosis was made with H-E, S-100 stain, and HMB-45 stain as a special stain.
Results: Histologically, there were Clark’s stage I for 3 patients, II in 4, III in 2, IV in 3, and stage V in 4 patients. The wide excision only greater than 2 ㎝margin was performed for 4 patients. The wide excision and lymph node
dissection were performed for 4 patients. The amputation was only performed for 3 patients, and the amputation and lymph node dissection were performed for 5 patients. After surgical excision, chemotherapy was done with Taxol for each 2 patients of stage IV and V. After long term follow-up for mean 4 years, 4 patients died related with melanoma, 1 patient was recurred, and 11 patients were cured.
Conclusion: The incidence of malignant melanoma was rare in Korea, but early involvement of lymph node at initial diagnosis was found in many cases (9/16, 56%). And then, early detec-tion and appropriated excision as well as careful dissection of adjacent lymph nodes will offer the patient the best chance for cure.
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KEYWORD
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Malignant melanoma, Surgical excision
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